Longevity Companies

Mitochondrial quality control. OPA1-OMA1 pathway

Berkeley, CA

mTORC1 inhibitors

Berkeley, CA

Young blood factors or drugs targeting these factors

San Carlos, CA

new biotechnology company focused on cellular rejuvenation programming to restore cell health and resilience, with the goal of reversing disease to transform medicine

Redwood City, CA

Clearing pathological cells with immunotherapy modalities

San Carlos, CA

Senotherapeutic that blocks transition from quiescence to senescence.

San Carlos, CA

Small molecules to break extracellular matrix crosslinks or prevent negative effects of crosslinks

Sherman Oaks, CA

Mitochondrial-derived peptides to treat metabolic and other diseases

Menlo Park, CA

Cyclodextrin drugs to block 7-ketocholesterol to treat heart disease. Formerly Underdog Pharma

Novato, CA

Immunotherapy to remove senescent cells

San Francisco, CA

Restore lysosomal functions to treat neurodegenerative diseases

South San Francisco, CA

Senoblocker for CAR-T cell expansion

San Carlos, CA

Cocoa analog to stimulate mitochondrial biogenesis

San Diego, CA

Mitochondrial uncoupler to treat obesity

San Francisco, CA

Nanoparticle delivered senolytic (fisetin)

Palo Alto, CA

Evvia is targeting mitochondrial dysfunction to create disease modifying treatments for devastating diseases, including Parkinson's and Alzheimer's diseases. small molecule activators for mitochondrial dysfunction (AMPK

Belmont, CA

Neutral blood exchange to rejuvenate tissues.

Mountain View, CA

Reversing thyme involution with a combination of therapies

Torrance, CA

Transcription factors to reverse diseases of aging

San Francisco, CA

Medical device to restore cerebrospinal fluid flow across the cribriform plate.

Riverside, CA

Dog life extension. IGF pathway

San Francisco, CA

Mitophagy drugs. PINK1 Parkin pathway

San Francisco, CA

Whole body mitochondrial transfer

Pleasanton, CA

Artificial nano-scavengers capable of depleting specific signalling molecules in blood.

Mill Valley, CA

Epigenetic reprogramming

South San Francisco, CA

Senolytic peptide for cosmetic and therapeutic use.

San Francisco, CA

Enhanced version of metformin. Target ion channel in complex I

San Francisco, CA

Gene therapies to extend lifespan of dogs

San Diego, CA

mRNA hTERT (telomerase)

Mountain View, CA

drug discovery for blood brain barrier repair, neurodegenerative disease using organoid model

Emeryville, CA

Single therapy for multiple age-related diseases

San Francisco, CA

Deuterated polyunsaturated fatty acids to protect against lipid peroxidation

Los Altos, CA

Enzymes that degrade glucosepane crosslink.

San Francisco, CA

Ablation of senescent cells and other pathological cells. Targeted prodrug approach?

Sunnyvale, CA

Epigenetic reprogramming with mRNA.

Mountain View, CA

Senolytics. Bcl-xL pathway and others

South San Francisco, CA

drug discovery platform company developing the next generation of induced-proximity medicine

San Francisco, CA

Young blood factors

Mountain View, CA

PAI-1 / apelin pathway for lifespan extension.

Los Angeles, CA