Longevity Biotech and Research Companies
What are the leading longevity biotech companies?
These biotechnology companies and research organizations work on the biology of aging, including cellular reprogramming, senolytics and geroscience. There are currently 176 listed.
Source: Longevity Intelligence Directory · Updated 2026-10-14
- 1.
- 2.ACM Global Laboratories
Rochester, NY
Bioanalytical, Central Lab Services U.S. locations: NY - Rochester.
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- 6.Aeovian Pharmaceuticals
San Francisco, CA
Biopharmaceutical company developing selective mTOR modulators for age-related and rare diseases.
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- 9.Alpha Genesis
Yemassee, SC
Nonhuman primate breeding, sales, bioproducts, and GLP toxicology research services U.S. locations: SC - Yemassee.
- 10.Altos Labs
Redwood City, CA
new biotechnology company focused on cellular rejuvenation programming to restore cell health and resilience, with the goal of reversing disease to transform medicine
- 11.Amerigo Scientific
Hauppauge, NY
Chromatography, ELISA, antigens, proteins, reagents, services U.S. locations: NY - Hauppauge.
- 12.
- 13.Animal Biosciences
Boston, MA
Lifespan extension for companion animals. Life Biosciences portfolio company
- 14.Antigen Targeting Consulting
Worcester, MA
Antibody production & services U.S. locations: MA - Worcester.
- 15.Aperture Therapeutics
San Carlos, CA
Delaying brain aging / curing neurodegenerative disease with diverse stem cell library based drug discovery platform + RNA therapeutics
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- 18.Assay Biotechnology
San Jose, CA
Antibodies, ELISA kits, Assays Kits, dyes, assay / antibody services U.S. locations: CA - San Jose.
- 19.Atropos Therapeutics
San Carlos, CA
Senotherapeutic that blocks transition from quiescence to senescence.
- 20.B2S Life Sciences
Franklin, IN
Biotherapeutic drug development company focused on improving bioanalytical methodology through reagent generation, Life-Cycle management, assay development and statistical analytics U.S. locations: IN - Franklin.
- 21.
- 22.Beantown Biotech
Billerica, MA
Contract Research services. Molecular Biology, Cell Biology, Biochemistry U.S. locations: MA - Billerica.
- 23.BioAge Labs
Berkeley, CA
Clinical-stage biotech using human biology to develop therapeutics that target the aging process, including metabolic diseases.
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- 26.BioTest4U
Covington, KY
Non-GLP preclinical testing of potential anti-cancer drugs in basic and more advanced tumor models U.S. locations: KY - Covington.
- 27.
- 28.Boston Matrix
Sherman Oaks, CA
Small molecules to break extracellular matrix crosslinks or prevent negative effects of crosslinks
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- 31.Calico Life Sciences
South San Francisco, CA
Alphabet-backed research and development company focused on understanding the biology of aging and developing interventions for age-related diseases.
- 32.Cambrian Biopharma
New York, NY
Diversified company building R&D platform, targeting multiple hallmarks of aging.
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- 36.Celerion
Lincoln, NE
Clinical Research U.S. locations: AZ - Tempe, NE - Lincoln, PA - West Conshohocken.
- 37.Centenara Labs
Limited public information available on this company.
- 38.Cleara Biotech
Amsterdam, Netherlands
Biotech company developing small-molecule senolytic drugs targeting senescent cells to treat age-related and fibrotic diseases.
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- 46.Crystal Bio Solutions
Cranbury, NJ
Bioanalytical services, biomarker discovery, CMC analytical services, and quantitative clinical pharmacology U.S. locations: NJ - Cranbury.
- 47.Cyclarity Therapeutics
Novato, CA
Cyclodextrin drugs to block 7-ketocholesterol to treat heart disease. Formerly Underdog Pharma
- 48.Cyclone Therapeutics
New York, NY
Proteostasis enhancement and integrated stress response mimetics. Cambrian Biopharma portfolio company
- 49.
- 50.Denali Therapeutics Inc.
South San Francisco, CA
Restore lysosomal functions to treat neurodegenerative diseases
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- 54.Eli Lilly and Company
Indianapolis, IN
Global pharmaceutical company developing medicines for diabetes, obesity, oncology, and neuroscience, including Zepbound and Mounjaro.
- 55.
- 56.Emery Pharma
Alameda, CA
CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals) U.S. locations: CA - Alameda.
- 57.EnClear Therapies
Newburyport, MA
Device based filtering and modifying of cerebrospinal fluid to treat neurodegenerative disease.
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- 62.Evvia Therapeutics
Belmont, CA
Evvia is targeting mitochondrial dysfunction to create disease modifying treatments for devastating diseases, including Parkinson's and Alzheimer's diseases. small molecule activators for mitochondrial dysfunction (AMPK
- 63.
- 64.Fountain Therapeutics
South San Francisco, CA
AI and computer vision platform to find drugs that reverse cellular aging
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- 66.
- 67.Gameto
Austin, TX
Therapies to treat menopause and reproductive aging. Reprogramming to make ovarian cells
- 68.Genflow Biosciences
London, United Kingdom
Biotechnology company developing gene therapies targeting the SIRT6 longevity gene to treat age-related metabolic diseases.
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- 70.
- 71.Gordian Biotechnology
South San Francisco, CA
Gene therapy based discovery platform aided with artificial intelligence.
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- 74.Helix Biostructures
Indianapolis, IN
CRO offering Cryo-EM, X-Ray Crystallography, Protein Production, LNP Characterization and SAXS U.S. locations: IN - Indianapolis.
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- 82.Inotiv
West Lafayette, IN
Contract lab services, Scientific Instruments U.S. locations: CO - Fort Collins, IN - West Lafayette, MO - St. Louis.
- 83.Integrated Pharma Services
Rockville, MD
Diagnostics and therapeutics services U.S. locations: MD - Rockville.
- 84.
- 85.Isterian Biotech
Brooklyn, NY
targeting transglutaminase 2 (TG2) to remove crosslinks and treat fibrosis
- 86.
- 87.
- 88.Juvena Therapeutics
Redwood City, CA
High throughput screening + computer vision ML to identify proteins that regenerate tissue
- 89.
- 90.KCAS Bioanlytical
Olathe, KS
KCAS Bio is a top CRO for bioanalytical and biomarker services globally. U.S. locations: KS - Kansas City, PA - Philadelphia.
- 91.
- 92.
- 93.Leucadia Therapeutics
Riverside, CA
Medical device to restore cerebrospinal fluid flow across the cribriform plate.
- 94.
- 95.Longaevus Technologies
London
Longaevus Technologies is a private research organisation based in Cambridge, UK that explores new and diverse pathways to healthy longevity.
- 96.
- 97.
- 98.Lysoclear
LaFayette, NY
Using bacterial enzymes to break down lipofuscin (waste that cannot be degraded by lysosomes)
- 99.
- 100.Matter Bioworks
Brooklyn, NY
Matter Bioworks is a longevity holding company focused on preserving genome integrity. Assets include Spellcheck Bio, MutagenTech, and Loki Therapeutics
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- 108.Nanotics
Mill Valley, CA
Artificial nano-scavengers capable of depleting specific signalling molecules in blood.
- 109.Napa Therapeutics
Drug that increases NAD+ levels
- 110.
- 111.NeuroAge Therapeutics
San Francisco, CA
Brain rejuvenation discovery platform based on post-mortem brain samples.
- 112.
- 113.NorthEast BioLab
Hamden, CT
Clinical, Preclinical, and Discovery Bioanalysis. PK, BA/BE, TK, immunogenicity (ADA), biomarker, and custom assays. U.S. locations: CT - Hamden.
- 114.
- 115.Novo Nordisk
Plainsboro, NJ
Danish pharmaceutical company known for diabetes, obesity, and metabolic disease treatments including GLP-1 medicines like Ozempic and Wegovy.
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- 118.Oisín Biotechnologies
Seattle, WA
Biotechnology company developing a programmable gene therapy platform to selectively destroy senescent cells.
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- 123.Panome Bio
St. Louis, MO
Metabolite, lipid, and protein screening services U.S. locations: MO - St. Louis.
- 124.
- 125.Ponce de Leon Health
Fernandina Beach, FL
Maker of Rejuvant Life Tabs, a calcium alpha-ketoglutarate supplement
- 126.
- 127.Pretzel Therapeutics
Waltham, MA
Targeting mitochondria genome, mtDNA express, and mitochondria quality control.
- 128.QPS
Newark, DE
QPS is a GLP/GCP-compliant global full-service CRO providing discovery, preclinical services, bioanalysis, clinical trials, and clinical drug development. We deliver custom-built research services in Pharmacology, Toxicology, DMPK, Bioanalysis, Cell Therapy Products, Clinical Tri
- 129.
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- 135.Rejuveron Life Sciences
Schlieren, Switzerland
Swiss biotech holding company developing therapeutics that target the biology of aging.
- 136.
- 137.Reservoir Neuroscience
Emeryville, CA
drug discovery for blood brain barrier repair, neurodegenerative disease using organoid model
- 138.
- 139.
- 140.Retrotope Inc.
Los Altos, CA
Deuterated polyunsaturated fatty acids to protect against lipid peroxidation
- 141.
- 142.Revivo Therapeutics
Durham, NC
Cognition enhancing drugs that target the CREB and nitric oxide pathways to treat CNS conditions including Alz, anxiety.
- 143.
- 144.Rubedo Life Sciences
Sunnyvale, CA
Ablation of senescent cells and other pathological cells. Targeted prodrug approach?
- 145.Samsara Therapeutics
Cambridge, MA
Biotechnology company developing autophagy-activating small molecules to treat neurodegenerative and age-related diseases.
- 146.Sannova Analytical
Somerset, NJ
Boutique CRO focused on Bioanalytical and Analytical CMC services from characterization to commercialization U.S. locations: NJ - Somerset.
- 147.Sapient Bioanalytics
San Diego, CA
Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation U.S. locations: CA - San Diego.
- 148.SBH Sciences
Natick, MA
A pre-clinical CRO specializing in protein production, cell-based assays, and bio-marker analysis. U.S. locations: MA - Natick.
- 149.
- 150.Selah Therapeutics
Ketone-based therapies for heart disease
- 151.
- 152.Shift Bioscience
Cambridge, United Kingdom
Biotech company using AI and machine learning to discover cellular rejuvenation therapeutics that reverse aging without dedifferentiation.
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- 156.Stealth BioTherapeutics Inc.
Needham, MA
Elamipretide peptide to stabilize cardiolipin and reduce peroxidation
- 157.Stemina Biomarker Discovery
Drug Screening & Development U.S. locations: WI - Madison.
- 158.Sword Bio
Large molecule assay development, validation and sample testing for PK, Biomarkers, Immunogenicity and Nab assays U.S. locations: IN - Carmel.
- 159.Synergy Bioscience
Analytical Chemistry, Microbiology U.S. locations: TX - Dallas.
- 160.
- 161.
- 162.Tempo Bioscience
Stem cell models, biosensor assay services, disease modeling U.S. locations: CA - San Francisco.
- 163.
- 164.TopoGEN
Assays, Antibodies, Cell Repair, Services U.S. locations: CO - Buena Vista.
- 165.Tornado Therapeutics
mTOR inhibitors
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- 167.
- 168.Turn Biotechnologies
Hayward, CA
Biotechnology company developing mRNA-based cellular rejuvenation therapies (ERA technology) to reverse aging at the cellular level.
- 169.Unity Biotechnology
South San Francisco, CA
Clinical-stage biopharmaceutical company developing senolytic medicines that selectively eliminate senescent cells to treat age-related diseases.
- 170.
- 171.
- 172.Weatherwax Bio
San Francisco, CA
drug discovery platform company developing the next generation of induced-proximity medicine
- 173.YouthBio
Cellular reprogramming
- 174.Yuva Biosciences
Birmingham, AL
Drugs to reverse wrinkles and fair loss. Reversible mtDNA mutation mouse
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