Longevity Companies

Mitochondrial quality control. OPA1-OMA1 pathway

Berkeley, CA

RNA Detection U.S. locations: CA - Newark.

Newark, CA

mTORC1 inhibitors

Berkeley, CA

Biopharmaceutical company developing selective mTOR modulators for age-related and rare diseases.

San Francisco, CA

Young blood factors or drugs targeting these factors

San Carlos, CA

new biotechnology company focused on cellular rejuvenation programming to restore cell health and resilience, with the goal of reversing disease to transform medicine

Redwood City, CA

Delaying brain aging / curing neurodegenerative disease with diverse stem cell library based drug discovery platform + RNA therapeutics

San Carlos, CA

Clearing pathological cells with immunotherapy modalities

San Carlos, CA

AI/ML drug discovery, pathology

San Francisco, CA

Antibodies, ELISA kits, Assays Kits, dyes, assay / antibody services U.S. locations: CA - San Jose.

San Jose, CA

Senotherapeutic that blocks transition from quiescence to senescence.

San Carlos, CA

Clinical-stage biotech using human biology to develop therapeutics that target the aging process, including metabolic diseases.

Berkeley, CA

Small molecules to break extracellular matrix crosslinks or prevent negative effects of crosslinks

Sherman Oaks, CA

Google's anti-aging subsidiary.

South San Francisco, CA

Alphabet-backed research and development company focused on understanding the biology of aging and developing interventions for age-related diseases.

South San Francisco, CA

Mitochondrial-derived peptides to treat metabolic and other diseases

Menlo Park, CA

Using space as an accelerating aging model for drug discovery

San Francisco, CA

Cyclodextrin drugs to block 7-ketocholesterol to treat heart disease. Formerly Underdog Pharma

Novato, CA

Immunotherapy to remove senescent cells

San Francisco, CA

Restore lysosomal functions to treat neurodegenerative diseases

South San Francisco, CA

Senoblocker for CAR-T cell expansion

San Carlos, CA

CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals) U.S. locations: CA - Alameda.

Alameda, CA

Contract Research & Services U.S. locations: CA - San Diego.

San Diego, CA

Cocoa analog to stimulate mitochondrial biogenesis

San Diego, CA

Mitochondrial uncoupler to treat obesity

San Francisco, CA

Nanoparticle delivered senolytic (fisetin)

Palo Alto, CA

Evvia is targeting mitochondrial dysfunction to create disease modifying treatments for devastating diseases, including Parkinson's and Alzheimer's diseases. small molecule activators for mitochondrial dysfunction (AMPK

Belmont, CA

Drug discovery from animal genomics and AI

Emeryville, CA

AI and computer vision platform to find drugs that reverse cellular aging

South San Francisco, CA

High-throughput phenotypic screening for drugs that extend lifespan

Novato, CA

Gene therapy based discovery platform aided with artificial intelligence.

South San Francisco, CA

Neutral blood exchange to rejuvenate tissues.

Mountain View, CA

Reversing thyme involution with a combination of therapies

Torrance, CA

Transcription factors to reverse diseases of aging

San Francisco, CA

High throughput screening + computer vision ML to identify proteins that regenerate tissue

Redwood City, CA

Medical device to restore cerebrospinal fluid flow across the cribriform plate.

Riverside, CA

Dog life extension. IGF pathway

San Francisco, CA

Mitophagy drugs. PINK1 Parkin pathway

San Francisco, CA

Whole body mitochondrial transfer

Pleasanton, CA

Artificial nano-scavengers capable of depleting specific signalling molecules in blood.

Mill Valley, CA

Brain rejuvenation discovery platform based on post-mortem brain samples.

San Francisco, CA

Epigenetic reprogramming

South San Francisco, CA

Senolytic peptide for cosmetic and therapeutic use.

San Francisco, CA

Enhanced version of metformin. Target ion channel in complex I

San Francisco, CA

Gene therapies to extend lifespan of dogs

San Diego, CA

mRNA hTERT (telomerase)

Mountain View, CA

drug discovery for blood brain barrier repair, neurodegenerative disease using organoid model

Emeryville, CA

Single therapy for multiple age-related diseases

San Francisco, CA

Deuterated polyunsaturated fatty acids to protect against lipid peroxidation

Los Altos, CA

Enzymes that degrade glucosepane crosslink.

San Francisco, CA

Ablation of senescent cells and other pathological cells. Targeted prodrug approach?

Sunnyvale, CA

Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation U.S. locations: CA - San Diego.

San Diego, CA

AI drug discovery

San Carlos, CA

Epigenetic reprogramming with mRNA.

Mountain View, CA

Biotechnology company developing mRNA-based cellular rejuvenation therapies (ERA technology) to reverse aging at the cellular level.

Hayward, CA

Clinical-stage biopharmaceutical company developing senolytic medicines that selectively eliminate senescent cells to treat age-related diseases.

South San Francisco, CA

Senolytics. Bcl-xL pathway and others

South San Francisco, CA

drug discovery platform company developing the next generation of induced-proximity medicine

San Francisco, CA

Young blood factors

Mountain View, CA

PAI-1 / apelin pathway for lifespan extension.

Los Angeles, CA

ML for anti-aging drug discovery

Emeryville, CA