Longevity Companies

Mitochondrial quality control. OPA1-OMA1 pathway

Berkeley, CA

RNA Detection U.S. locations: CA - Newark.

Newark, CA

Los Angeles, CA

San Jose, CA

mTORC1 inhibitors

Berkeley, CA

Biopharmaceutical company developing selective mTOR modulators for age-related and rare diseases.

San Francisco, CA

Los Angeles, CA

embryonic stem cell progenitors and induced-tissue regeneration

Alameda, CA

Life sciences company developing ultra-sensitive proteomics technology (NULISA) for biomarker detection.

Fremont, CA

Clinical-stage biotechnology company developing immuno-neurology therapies for neurodegenerative diseases like Alzheimer's.

South San Francisco, CA

Young blood factors or drugs targeting these factors

San Carlos, CA

Pasadena, CA

Sherman Oaks, CA

new biotechnology company focused on cellular rejuvenation programming to restore cell health and resilience, with the goal of reversing disease to transform medicine

Redwood City, CA

San Diego, CA

Culver City, CA

Valley Village, CA

Bakersfield, CA

Anaheim, CA

Delaying brain aging / curing neurodegenerative disease with diverse stem cell library based drug discovery platform + RNA therapeutics

San Carlos, CA

Global technology company producing the Apple Watch, which includes health and fitness tracking features such as heart rate and sleep monitoring.

Cupertino, CA

Biological age testing company offering epigenetic clock-based blood tests to measure biological aging rate.

San Francisco, CA

Clearing pathological cells with immunotherapy modalities

San Carlos, CA

AI/ML drug discovery, pathology

San Francisco, CA

Biotechnology company developing autologous, personalized cell therapies for Parkinson's disease.

San Diego, CA

Antibodies, ELISA kits, Assays Kits, dyes, assay / antibody services U.S. locations: CA - San Jose.

San Jose, CA

AI-driven drug discovery company using deep learning to predict small molecule binding for new therapeutics.

San Francisco, CA

Senotherapeutic that blocks transition from quiescence to senescence.

San Carlos, CA

La Jolla, CA

Bakersfield, CA

Clinical-stage biotech using human biology to develop therapeutics that target the aging process, including metabolic diseases.

Berkeley, CA

Comprehensive executive longevity assessment clinic.

San Mateo, CA

Medical clinic / wellness center in Woodland Hills (LA market); alternative medicine practitioner services. Medical oversight unconfirmed.

Woodland Hills, CA

Modulating alternative splicing factors . Formerly Samumed.

San Diego, CA

Wearable health technology company producing biometric tracking devices for sleep, recovery, and clinical-grade health monitoring.

Los Angeles, CA

Sacramento, CA

Small molecules to break extracellular matrix crosslinks or prevent negative effects of crosslinks

Sherman Oaks, CA

Sleep technology company developing the Restorative Bed, an AI-driven smart mattress that actively adapts to improve sleep.

Los Altos, CA

Google's anti-aging subsidiary.

South San Francisco, CA

Alphabet-backed research and development company focused on understanding the biology of aging and developing interventions for age-related diseases.

South San Francisco, CA

San Francisco, CA

Oakland, CA

Long Beach, CA

Mitochondrial-derived peptides to treat metabolic and other diseases

Menlo Park, CA

Using space as an accelerating aging model for drug discovery

San Francisco, CA

San Francisco, CA

Cyclodextrin drugs to block 7-ketocholesterol to treat heart disease. Formerly Underdog Pharma

Novato, CA

Immunotherapy to remove senescent cells

San Francisco, CA

Biotechnology company developing therapies for neurodegenerative diseases using its blood-brain barrier crossing platform.

South San Francisco, CA

Restore lysosomal functions to treat neurodegenerative diseases

South San Francisco, CA

Medical device company that develops and manufactures continuous glucose monitoring (CGM) systems for diabetes and metabolic health management.

San Diego, CA

Los Angeles, CA

Senoblocker for CAR-T cell expansion

San Carlos, CA

Los Angeles, CA

Woodland Hills, CA

Los Angeles, CA

CRO supporting discovery for small molecules, biologics (mAbs, ADCs, gene therapy, botanicals) U.S. locations: CA - Alameda.

Alameda, CA

Contract Research & Services U.S. locations: CA - San Diego.

San Diego, CA

Cocoa analog to stimulate mitochondrial biogenesis

San Diego, CA

Mitochondrial uncoupler to treat obesity

San Francisco, CA

Clinical-stage biotech developing non-viral mRNA cell engineering and immunotherapy platforms.

San Diego, CA

Nanoparticle delivered senolytic (fisetin)

Palo Alto, CA

Long Beach, CA

Irvine, CA

Evvia is targeting mitochondrial dysfunction to create disease modifying treatments for devastating diseases, including Parkinson's and Alzheimer's diseases. small molecule activators for mitochondrial dysfunction (AMPK

Belmont, CA

Los Angeles, CA

Drug discovery from animal genomics and AI

Emeryville, CA

Medical weight-loss program offering GLP-1 and other prescriptions plus coaching.

San Francisco, CA

AI and computer vision platform to find drugs that reverse cellular aging

South San Francisco, CA

Biotechnology company developing blood-based cancer screening tests powered by machine learning and multiomics platforms.

South San Francisco, CA

Fair Oaks, CA

North Hollywood, CA

North Hollywood, CA

Los Angeles, CA

San Jose, CA

Los Angeles, CA

High-throughput phenotypic screening for drugs that extend lifespan

Novato, CA

Gene therapy based discovery platform aided with artificial intelligence.

South San Francisco, CA

Healthcare company developing the Galleri multi-cancer early detection blood test using genomic sequencing and machine learning.

Menlo Park, CA

Precision oncology company developing blood-based liquid biopsy tests for cancer detection, monitoring, and treatment selection.

Palo Alto, CA

Poway, CA

Los Angeles, CA

Direct-to-consumer telehealth provider of GLP-1 weight-loss treatment.

Los Angeles, CA

Consumer telehealth platform offering GLP-1 and personalized weight-loss treatment.

San Francisco, CA

Digital musculoskeletal health company providing technology-enabled physical therapy programs for chronic pain and injury.

San Francisco, CA

Bakersfield, CA

Genomics-based health intelligence company offering comprehensive health and longevity assessments combining genomics and imaging.

San Diego, CA

San Diego, CA

South San Francisco, CA

Longevity-focused concierge health platform providing personalized preventive care and executive health programs.

San Francisco, CA

Irvine, CA

Neutral blood exchange to rejuvenate tissues.

Mountain View, CA

Glendale, CA

Clinical-stage biotechnology company using generative AI to accelerate drug discovery and development, including for aging-related diseases.

Brisbane, CA

Playa Del Rey, CA

Santa Monica, CA

Reversing thyme involution with a combination of therapies

Torrance, CA

Los Angeles, CA

Los Angeles, CA

Glendale, CA

AI-powered nutrition and metabolic health platform.

Menlo Park, CA

Medical clinic / medical spa / wellness center in Chatsworth (LA market). Medical oversight: Yes.

Chatsworth, CA

Pasadena, CA

Transcription factors to reverse diseases of aging

San Francisco, CA

High throughput screening + computer vision ML to identify proteins that regenerate tissue

Redwood City, CA

Medical device to restore cerebrospinal fluid flow across the cribriform plate.

Riverside, CA

Health optimization platform founded by Tony Robbins offering diagnostics, hormones and supplements.

Santa Monica, CA

Southern California medical weight-loss clinics offering GLP-1 treatment.

Costa Mesa, CA

Clinical-stage biotechnology company developing allogeneic cell therapy products for degenerative retinal and neurological conditions.

Carlsbad, CA

Allogeneic cell transplants for regeneration.

Carlsbad, CA

San Diego, CA

Norwalk, CA

San Francisco, CA

Sacramento, CA

Newport Beach, CA

Recovery hub / medical spa in Los Angeles. Medical oversight listed.

Los Angeles, CA

San Diego, CA

Los Angeles, CA

Los Gatos, CA

Mission Viejo, CA

San Diego, CA

Orange, CA

Rancho Santa Fe, CA

Los Angeles, CA

Granite Bay, CA

Dog life extension. IGF pathway

San Francisco, CA

Fresno, CA

San Francisco, CA

Los Angeles, CA

Virtual care for women in midlife, including menopause and GLP-1 weight care.

San Francisco, CA

Healthy aging coaching platform.

San Francisco, CA

Mitophagy drugs. PINK1 Parkin pathway

San Francisco, CA

Whole body mitochondrial transfer

Pleasanton, CA

Obesity medicine telehealth practice offering GLP-1 care and nutrition support.

San Francisco, CA

Drugs to regenerate muscle through activation of muscle stem cells.

Menlo Park, CA

Artificial nano-scavengers capable of depleting specific signalling molecules in blood.

Mill Valley, CA

Brain rejuvenation discovery platform based on post-mortem brain samples.

San Francisco, CA

Epigenetic reprogramming

South San Francisco, CA

Preventive health optimization clinics.

Los Angeles, CA

Digital health company offering virtual care programs for chronic disease prevention and management, including diabetes and metabolic health.

San Francisco, CA

Senolytic peptide for cosmetic and therapeutic use.

San Francisco, CA

Fresno, CA

Fresno, CA

Biotechnology company developing 3D bioprinted human tissues for therapeutic and research applications.

San Diego, CA

Bakersfield, CA

Enhanced version of metformin. Target ion channel in complex I

San Francisco, CA

Long Beach, CA

Engineering gut microbes to secrete therapeutic metabolites to treat metabolic disease and extend lifespan.

Torrance, CA

Virtual primary care offering medical weight-loss and GLP-1 prescriptions.

San Francisco, CA

Neuroscience company that develops BrainHQ, a clinically-validated brain training program to improve cognitive function.

San Francisco, CA

Beverly Hills, CA

Fresno, CA

Whole-body preventive health scanning.

San Carlos, CA

Los Angeles functional and integrative medicine with nutritional therapy and hormone optimization.

Los Angeles, CA

Long Beach, CA

Medical clinic / wellness center + medical spa in Sherman Oaks (LA market). Medical oversight: Yes.

Sherman Oaks, CA

Gene therapies to extend lifespan of dogs

San Diego, CA

Medical clinic / wellness center in Los Angeles.

Los Angeles, CA

mRNA hTERT (telomerase)

Mountain View, CA

Beverly Hills, CA

San Jose, CA

Los Angeles, CA

drug discovery for blood brain barrier repair, neurodegenerative disease using organoid model

Emeryville, CA

Medical device company developing cloud-connected devices for sleep apnea, respiratory care, and sleep health management.

San Diego, CA

Single therapy for multiple age-related diseases

San Francisco, CA

Deuterated polyunsaturated fatty acids to protect against lipid peroxidation

Los Altos, CA

Enzymes that degrade glucosepane crosslink.

San Francisco, CA

Sacramento, CA

Woodland Hills clinic offering IV therapy and pain management.

Woodland Hills, CA

Wearable technology company producing a smart ring that tracks sleep, activity, and health metrics.

San Jose, CA

Holistic practitioner offering chiropractic care, applied clinical nutrition and functional medicine (Los Angeles and Toronto).

Los Angeles, CA

Ablation of senescent cells and other pathological cells. Targeted prodrug approach?

Sunnyvale, CA

Multi-omics biomarker discovery – metabolomics, lipidomics, proteomics, bioinformatics & translation U.S. locations: CA - San Diego.

San Diego, CA

Life sciences company developing proteomics technology platforms to unlock the proteome for biomarker discovery.

Redwood City, CA

Metabolic health company combining continuous glucose monitors with an app to provide personalized weight and metabolic insights.

Palo Alto, CA

Sleep technology company providing contactless sleep tracking technology and personalized sleep improvement programs.

San Diego, CA

Los Angeles, CA

Sleep technology company producing an AI-driven neurostimulation headband designed to improve sleep quality.

Los Angeles, CA

AI drug discovery

San Carlos, CA

Bakersfield, CA

Fitness technology company producing an AI-powered smart home gym system with 3D sensors for real-time form tracking.

San Francisco, CA

Fresno, CA

San Francisco, CA

Fresno, CA

Tarzana, CA

Fitness technology company that makes a smart home gym system using digital weight resistance and AI-driven coaching.

San Francisco, CA

Wellness center in Los Angeles; medical-clinic category listing.

Los Angeles, CA

Epigenetic reprogramming with mRNA.

Mountain View, CA

Biotechnology company developing mRNA-based cellular rejuvenation therapies (ERA technology) to reverse aging at the cellular level.

Hayward, CA

Santa Ana, CA

Digital health company using a Whole Body Digital Twin technology to reverse chronic metabolic diseases like diabetes.

San Mateo, CA

Los Angeles, CA

Clinical-stage biopharmaceutical company developing senolytic medicines that selectively eliminate senescent cells to treat age-related diseases.

South San Francisco, CA

Senolytics. Bcl-xL pathway and others

South San Francisco, CA

AI company developing digital twin technology to generate synthetic control arms for clinical trials.

Emeryville, CA

Digital health company providing a clinically-proven treatment for type 2 diabetes and metabolic health reversal through nutritional therapy.

San Francisco, CA

Sherman Oaks, CA

drug discovery platform company developing the next generation of induced-proximity medicine

San Francisco, CA

San Francisco, CA

Personalized biomarker testing and wellness platform.

San Francisco, CA

Biotechnology company using AI-driven protein design and generative models to discover and develop new drugs.

Palo Alto, CA

Gene therapy to stimulate cardiac tissue regeneration

Laguna Hills, CA

Young blood factors

Mountain View, CA

Technology company that manufactures Amazfit smartwatches and health-tracking wearable devices.

Cupertino, CA

PAI-1 / apelin pathway for lifespan extension.

Los Angeles, CA

ML for anti-aging drug discovery

Emeryville, CA

Fullerton, CA

Healthy aging supplement company.

San Francisco, CA